with 9 state-of-the-art technological platforms
When our staff provides significant scientific insights, they are invited to co-author the publication. Additionally, we occasionally publish papers on methodologies and provide various resources.
2024
Boisserand, L. S. B., Geraldo, L. H., Bouchart, J., El Kamouh, M.-R., Lee, S., Sanganahalli, B. G., Spajer, M., Zhang, S., Lee, S., Parent, M., Xue, Y., Skarica, M., Yin, X., Guegan, J., Boyé, K., Saceanu Leser, F., Jacob, L., Poulet, M., Li, M., … Thomas, J.-L. (2024). VEGF-C prophylaxis favors lymphatic drainage and modulates neuroinflammation in a stroke model. Journal of Experimental Medicine, 221(4), e20221983. https://doi.org/10.1084/jem.20221983
Brideau, G., Cheval, L., Griveau, C., Ling, W.-M. E., Lievre, L., Crambert, G., Müller, D., Broćić, J., Cherchame, E., Houillier, P., & Prot-Bertoye, C. (2024). Claudin-10 Expression and the Gene Expression Pattern of Thick Ascending Limb Cells. International Journal of Molecular Sciences, 25(7), 4008. https://doi.org/10.3390/ijms25074008
Chougar, L., Faucher, A., Faouzi, J., Lejeune, F., Gama Lobo, G., Jovanovic, C., Cormier, F., Dupont, G., Vidailhet, M., Corvol, J., Colliot, O., Lehéricy, S., Grabli, D., & Degos, B. (2024). Contribution of MRI for the Early Diagnosis of Parkinsonism in Patients with Diagnostic Uncertainty. Movement Disorders, mds.29760. https://doi.org/10.1002/mds.29760
Kacher, R., Lejeune, F.-X., David, I., Boluda, S., Coarelli, G., Leclere-Turbant, S., Heinzmann, A., Marelli, C., Charles, P., Goizet, C., Kabir, N., Hilab, R., Jornea, L., Six, J., Dommergues, M., Fauret, A.-L., Brice, A., Humbert, S., & Durr, A. (2024). CAG repeat mosaicism is gene specific in spinocerebellar ataxias. The American Journal of Human Genetics. https://doi.org/10.1016/j.ajhg.2024.03.015
Menon, P. J., Sambin, S., Criniere-Boizet, B., Courtin, T., Tesson, C., Casse, F., Ferrien, M., Mariani, L.-L., Carvalho, S., Lejeune, F.-X., Rebbah, S., Martet, G., Houot, M., Lanore, A., Mangone, G., Roze, E., Vidailhet, M., Aasly, J., Gan Or, Z., … French Parkinson disease Genetics Study Group (PDG). (2024). Genotype–phenotype correlation in PRKN-associated Parkinson’s disease. Npj Parkinson’s Disease, 10(1), 72. https://doi.org/10.1038/s41531-024-00677-3
Rohaut, B., Calligaris, C., Hermann, B., Perez, P., Faugeras, F., Raimondo, F., King, J.-R., Engemann, D., Marois, C., Le Guennec, L., Di Meglio, L., Sangaré, A., Munoz Musat, E., Valente, M., Ben Salah, A., Demertzi, A., Belloli, L., Manasova, D., Jodaitis, L., … Naccache, L. (2024). Multimodal assessment improves neuroprognosis performance in clinically unresponsive critical-care patients with brain injury. Nature Medicine, 1–7. https://doi.org/10.1038/s41591-024-03019-1
Ronzano, R., Perrot, C., Mazuir, E., Thetiot, M., Aigrot, M.-S., Stheneur, P., Lejeune, F.-X., Stankoff, B., Lubetzki, C., Sol-Foulon, N., & Desmazières, A. (2024). Neuronal activity promotes axonal node-like clustering prior to myelination and remyelination in the central nervous system (p. 2024.03.16.585168). bioRxiv. https://doi.org/10.1101/2024.03.16.585168
2023
Casse, F., Courtin, T., Tesson, C., Ferrien, M., Noël, S., Fauret‐Amsellem, A., Gareau, T., Guegan, J., Anheim, M., Mariani, L., Le Forestier, N., Tranchant, C., Corvol, J., Lesage, S., Brice, A., & for the French Parkinson’s disease genetics study group (PDG). (2023). Detection of ATXN2 Expansions in an Exome Dataset: An Underdiagnosed Cause of Parkinsonism. Movement Disorders Clinical Practice, 10(4), 664–669. https://doi.org/10.1002/mdc3.13699
Chougar, L., Lejeune, F.-X., Faouzi, J., Morino, B., Faucher, A., Hoyek, N., Grabli, D., Cormier, F., Vidailhet, M., Corvol, J.-C., Colliot, O., Degos, B., & Lehéricy, S. (2023). Comparison of mean diffusivity, R2* relaxation rate and morphometric biomarkers for the clinical differentiation of parkinsonism. Parkinsonism & Related Disorders, 108, 105287. https://doi.org/10.1016/j.parkreldis.2023.105287
Courtin, C., Marie-Claire, C., Gross, G., Hennion, V., Mundwiller, E., Guégan, J., Meyrel, M., Bellivier, F., & Etain, B. (2023). Gene expression of circadian genes and CIART in bipolar disorder: A preliminary case-control study. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 122, 110691. https://doi.org/10.1016/j.pnpbp.2022.110691
Gassama, S., Garmendia, A., Lejeune, F. X., Boudot de la Motte, M., Louapre, C., Papeix, C., Maillart, E., & Roux, T. (2023). A short washout period from fingolimod to anti-CD20 therapy is safe and decreases the risk of reactivation. Revue Neurologique, 179(9), 1035–1038. https://doi.org/10.1016/j.neurol.2023.03.028
Genovese, G., Diaz-Fernandez, B., Lejeune, F.-X., Ronen, I., Marjańska, M., Yahia-Cherif, L., Lehéricy, S., Branzoli, F., & Rosso, C. (2023). Longitudinal Monitoring of Microstructural Alterations in Cerebral Ischemia with in Vivo Diffusion-weighted MR Spectroscopy. Radiology, 306(3), e220430. https://doi.org/10.1148/radiol.220430
Guieysse, T., Lamothe, R., Houot, M., Razafimahatratra, S., Medani, T., Lejeune, F.-X., Dreyfus, G., Klarsfeld, A., Pantazis, D., Koechlin, E., & Andrade, K. (2023). Detecting Anosognosia from the Prodromal Stage of Alzheimer’s Disease. Journal of Alzheimer’s Disease, 95(4), 1723–1733. https://doi.org/10.3233/JAD-230552
Heinzmann, A., Sayah, S., Lejeune, F.-X., Hahn, V., Teichmann, M., Monin, M.-L., Marchionni, E., Gérard, F., Charles, P., Pariente, J., & Durr, A. (2023). Huntington’s Disease with Small CAG Repeat Expansions. Movement Disorders, 38(7), 1294–1306. https://doi.org/10.1002/mds.29427
Lakhlifi, C., Lejeune, F.-X., Rouault, M., Khamassi, M., & Rohaut, B. (2023). Illusion of knowledge in statistics among clinicians: Evaluating the alignment between objective accuracy and subjective confidence, an online survey. Cognitive Research: Principles and Implications, 8(1), 23. https://doi.org/10.1186/s41235-023-00474-1
Lamothe, H., Schreiweis, C., Mondragón-González, L. S., Rebbah, S., Lavielle, O., Mallet, L., & Burguière, E. (2023). The Sapap3−/− mouse reconsidered as a comorbid model expressing a spectrum of pathological repetitive behaviours. Translational Psychiatry, 13(1), 26. https://doi.org/10.1038/s41398-023-02323-7
Lerond, J., Mathon, B., Scopin, M., Nichelli, L., Guégan, J., Bertholle, C., Izac, B., Andrieu, M., Gareau, T., Donneger, F., Mohand Oumoussa, B., Letourneur, F., Tran, S., Bertrand, M., Le Roux, I., Touat, M., Dupont, S., Poncer, J. C., Navarro, V., & Bielle, F. (2023). Hippocampal and neocortical BRAF mutant non-expansive lesions in focal epilepsies. Neuropathology and Applied Neurobiology, 49(5), e12937. https://doi.org/10.1111/nan.12937
Nobileau, A., Gaurav, R., Chougar, L., Faucher, A., Valabrègue, R., Mangone, G., Leu‐Semenescu, S., Lejeune, F., Corvol, J., Arnulf, I., Vidailhet, M., Grabli, D., Degos, B., & Lehéricy, S. (2023). Neuromelanin‐Sensitive Magnetic Resonance Imaging Changes in the Locus Coeruleus/Subcoeruleus Complex in Patients with Typical and Atypical Parkinsonism. Movement Disorders, 38(3), 479–484. https://doi.org/10.1002/mds.29309
Prendergast, A. E., Jim, K. K., Marnas, H., Desban, L., Quan, F. B., Djenoune, L., Laghi, V., Hocquemiller, A., Lunsford, E. T., Roussel, J., Keiser, L., Lejeune, F.-X., Dhanasekar, M., Bardet, P.-L., Levraud, J.-P., Van De Beek, D., Vandenbroucke-Grauls, C. M. J. E., & Wyart, C. (2023). CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection. Current Biology, 33(5), 940-956.e10. https://doi.org/10.1016/j.cub.2023.01.039
Razafimahatratra, S., Guieysse, T., Lejeune, F.-X., Houot, M., Medani, T., Dreyfus, G., Klarsfeld, A., Villain, N., Pereira, F. R., La Corte, V., George, N., Pantazis, D., & Andrade, K. (2023). Can a failure in the error-monitoring system explain unawareness of memory deficits in Alzheimer’s disease? Cortex, 166, 428–440. https://doi.org/10.1016/j.cortex.2023.05.014
Salam, R., Saliou, A., Bielle, F., Bertrand, M., Antoniewski, C., Carpentier, C., Alentorn, A., Capelle, L., Sanson, M., Huillard, E., Bellenger, L., Guégan, J., & Le Roux, I. (2023). Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma. Nature Communications, 14(1), 441. https://doi.org/10.1038/s41467-023-36124-9
Shor, N., Lamirel, C., Rebbah, S., Vignal, C., Vasseur, V., Savatovsky, J., de la Motte, M. B., Gout, O., Lecler, A., Hage, R., & Deschamps, R. (2023). High diagnostic accuracy of T2FLAIR at 3 T in the detection of optic nerve head edema in acute optic neuritis. European Radiology. https://doi.org/10.1007/s00330-023-10139-8
Simoes Braga Boisserand, L., Bouchart, J., Geraldo, L. H., Lee, S., Sanganahalli, B. G., Parent, M., Zhang, S., Xue, Y., Skarica, M., Guegan, J., Li, M., Liu, X., Poulet, M., Askanase, M., Osherov, A., Spajer, M., Kamouh, M.-R. E., Eichmann, A., Alitalo, K., … Thomas, J.-L. (2023). VEGF-C promotes brain-derived fluid drainage, confers neuroprotection, and improves stroke outcomes [Preprint]. Neuroscience. https://doi.org/10.1101/2023.05.30.542708
Xu, H., Dugué, G. P., Cantaut-Belarif, Y., Lejeune, F.-X., Gupta, S., Wyart, C., & Lehtinen, M. K. (2023). SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation. Fluids and Barriers of the CNS, 20(1), 89. https://doi.org/10.1186/s12987-023-00491-8
Tanaka, A., Sèdes, A., Bonardi, A., Whitmarsh, S., Fierro, D., & Maggio, F. D. (2023, May 16). Brain-Body Digital Musical Instrument Work-in-Progress. ISEA 2023 – 28th International Symposium on Electronic Art. https://hal.science/hal-04259596
Maggio, F. D., Tanaka, A., Fierro, D., & Whitmarsh, S. (2023, August 30). An Interactive Modular System for Electrophysiological DMIs. Audio mostly 2023. https://doi.org/10.1145/3616195.3616226
Valabregue, R., Girka, F., Pron, A., Rousseau, F., & Auzias, G. (2023, September 11). Comprehensive analysis of synthetic learning applied to neonatal brain MRI segmentation. arXiv.Org. https://arxiv.org/abs/2309.05306v1
2022
Chougar, L., Arsovic, E., Gaurav, R., Biondetti, E., Faucher, A., Valabrègue, R., Pyatigorskaya, N., Dupont, G., Lejeune, F., Cormier, F., Corvol, J., Vidailhet, M., Degos, B., Grabli, D., & Lehéricy, S. (2022). Regional Selectivity of Neuromelanin Changes in the Substantia Nigra in Atypical Parkinsonism. Movement Disorders, 37(6), 1245–1255. https://doi.org/10.1002/mds.28988
Daruich, A., Picard, E., Guégan, J., Jaworski, T., Parenti, L., Delaunay, K., Naud, M.-C., Berdugo, M., Boatright, J. H., & Behar-Cohen, F. (2022). Comparative Analysis of Urso- and Tauroursodeoxycholic Acid Neuroprotective Effects on Retinal Degeneration Models. Pharmaceuticals, 15(3), 334. https://doi.org/10.3390/ph15030334
Fouad, A., Azizollahi, H., Le Douget, J. E., Lejeune, F. X., Valderrama, M., Mayor, L., NAVARRO, V., & Le Van Quyen, M. (2022). Interictal epileptiform discharges show distinct spatiotemporal and morphological patterns across wake and sleep. Brain Communications, fcac183. https://doi.org/10.1093/braincomms/fcac183
Kmetzsch, V., Latouche, M., Saracino, D., Rinaldi, D., Camuzat, A., Gareau, T., the French Research Network on FTD/ALS, Le Ber, I., Colliot, O., & Becker, E. (2022). MicroRNA signatures in genetic frontotemporal dementia and amyotrophic lateral sclerosis. Annals of Clinical and Translational Neurology, acn3.51674. https://doi.org/10.1002/acn3.51674
Lei, L., Bruneau, A., El Mourabit, H., Guégan, J., Folseraas, T., Lemoinne, S., Karlsen, T. H., Hoareau, B., Morichon, R., Gonzalez‐Sanchez, E., Goumard, C., Ratziu, V., Charbord, P., Gautheron, J., Tacke, F., Jaffredo, T., Cadoret, A., & Housset, C. (2022). Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis. Hepatology, hep.32456. https://doi.org/10.1002/hep.32456
Lejeune, F.-X., Ichou, F., Camenen, E., Colsch, B., Mauger, F., Peltier, C., Moszer, I., Gilson, E., Pierre-Jean, M., Floch, E. L., Sabarly, V., Tenenhaus, A., Deleuze, J.-F., Ewenczyk, C., Vidailhet, M., & Mochel, F. (2022). A Multimodal Omics Exploration of the Motor and Non-Motor Symptoms of Parkinson’s Disease. International Journal of Translational Medicine, 2(1), 97–112. https://doi.org/10.3390/ijtm2010009
Orts‐Del’Immagine, A., Dhanasekar, M., Lejeune, F., Roussel, J., & Wyart, C. (2022). A norepinephrine‐dependent glial calcium wave travels in the spinal cord upon acoustovestibular stimuli. Glia, 70(3), 491–507. https://doi.org/10.1002/glia.24118
Parodi, L., Barbier, M., Jacoupy, M., Pujol, C., Lejeune, F.-X., Lallemant-Dudek, P., Esteves, T., Pennings, M., Kamsteeg, E.-J., Guillaud-Bataille, M., Banneau, G., Coarelli, G., Oumoussa, B. M., Fraidakis, M. J., Stevanin, G., Depienne, C., van de Warrenburg, B., Brice, A., & Durr, A. (2022). The mitochondrial seryl-tRNA synthetase SARS2 modifies onset in spastic paraplegia type 4. Genetics in Medicine: Official Journal of the American College of Medical Genetics, S1098-3600(22)00875-9. https://doi.org/10.1016/j.gim.2022.07.023
Peltier, C., Lejeune, F.-X., Jorgensen, L. G. T., Rametti-Lacroux, A., Tanguy, D., Godefroy, V., Bendetowicz, D., Carle, G., Cognat, E., Bombois, S., Migliaccio, R., Levy, R., Marin, F., Batrancourt, B., & ECOCAPTURE study group. (2022). A temporal classification method based on behavior time series data in patients with behavioral variant of frontotemporal dementia and apathy. Journal of Neuroscience Methods, 376, 109625. https://doi.org/10.1016/j.jneumeth.2022.109625
Razafimahatratra, S., Guieysse, T., Lejeune, F.-X., Houot, M., Medani, T., Dreyfus, G., Klarsfeld, A., Villain, N., Pereira, F. R., Corte, V. L., George, N., Pantazis, D., & Andrade, K. (2022). Can a failure in the error monitoring system explain unawareness of memory deficits in Alzheimer’s disease? [Preprint]. In Review. https://doi.org/10.21203/rs.3.rs-1577671/v1
Xicota, L., Gyorgy, B., Grenier-Boley, B., Lecoeur, A., Fontaine, G., Danjou, F., Gonzalez, J. S., Colliot, O., Amouyel, P., Martin, G., Levy, M., Villain, N., Habert, M.-O., Dubois, B., Lambert, J.-C., Potier, M.-C., & on behalf of the INSIGHT pre-AD study group and for the Alzheimer’s Disease Neuroimaging Initiative. (2022). Association of APOE -Independent Alzheimer Disease Polygenic Risk Score With Brain Amyloid Deposition in Asymptomatic Older Adults. Neurology, 99(5), e462–e475. https://doi.org/10.1212/WNL.0000000000200544
2021
Archontidi, S., Marie, C., Gyorgy, B., Guegan, J., Sanson, M., Parras, C., & Huillard, E. (2021). TCF12 controls oligodendroglial cell proliferation and regulates signaling pathways conserved in gliomas [Preprint]. Neuroscience. https://doi.org/10.1101/2021.07.26.453859
Berdugo, M., Delaunay, K., Naud, M.-C., Guegan, J., Moulin, A., Savoldelli, M., Picard, E., Radet, L., Jonet, L., Djerada, Z., Gozalo, C., Daruich, A., Beltrand, J., Jeanny, J.-C., Kermorvant-Duchemin, E., Crisanti, P., Polak, M., & Behar-Cohen, F. (2021). The antidiabetic drug glibenclamide exerts direct retinal neuroprotection. Translational Research, 229, 83–99. https://doi.org/10.1016/j.trsl.2020.10.003
Boeri, J., Meunier, C., Le Corronc, H., Branchereau, P., Timofeeva, Y., Lejeune, F.-X., Mouffle, C., Arulkandarajah, H., Mangin, J. M., Legendre, P., & Czarnecki, A. (2021). Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity. ELife, 10, e62639. https://doi.org/10.7554/eLife.62639
Canonica, J., Zhao, M., Favez, T., Gelizé, E., Jonet, L., Kowalczuk, L., Guegan, J., Le Menuet, D., Viengchareun, S., Lombès, M., Pussard, E., Arsenijevic, Y., & Behar-Cohen, F. (2021). Pathogenic Effects of Mineralocorticoid Pathway Activation in Retinal Pigment Epithelium. International Journal of Molecular Sciences, 22(17), 9618. https://doi.org/10.3390/ijms22179618
Combette, L. T., Camenen, E., Rotge, J.-Y., & Schmidt, L. (2021). Identified Motivation as a Key Factor for School Engagement During the COVID-19 Pandemic-Related School Closure. Frontiers in Psychology, 12, 752650. https://doi.org/10.3389/fpsyg.2021.752650
Kacher, R., Lejeune, F.-X., Noël, S., Cazeneuve, C., Brice, A., Humbert, S., & Durr, A. (2021). Propensity for somatic expansion increases over the course of life in Huntington disease. ELife, 10, e64674. https://doi.org/10.7554/eLife.64674
Kmetzsch, V., Anquetil, V., Saracino, D., Rinaldi, D., Camuzat, A., Gareau, T., Jornea, L., Forlani, S., Couratier, P., Wallon, D., Pasquier, F., Robil, N., de la Grange, P., Moszer, I., Le Ber, I., Colliot, O., & Becker, E. (2021). Plasma microRNA signature in presymptomatic and symptomatic subjects with C9orf72 -associated frontotemporal dementia and amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery & Psychiatry, 92(5), 485–493. https://doi.org/10.1136/jnnp-2020-324647
Lemercier, P., Vergallo, A., Lista, S., Zetterberg, H., Blennow, K., Potier, M.-C., Habert, M.-O., Lejeune, F.-X., Dubois, B., Teipel, S., & Hampel, H. (2021). Association of plasma Aβ40/Aβ42 ratio and brain Aβ accumulation: Testing a whole-brain PLS-VIP approach in individuals at risk of Alzheimer’s disease. Neurobiology of Aging, 107, 57–69. https://doi.org/10.1016/j.neurobiolaging.2021.07.005
Muratet, F., Teyssou, E., Chiot, A., Boillée, S., Lobsiger, C. S., Bohl, D., Gyorgy, B., Guegan, J., Marie, Y., Amador, M. del M., Salachas, F., Meininger, V., Bernard, E., Antoine, J.-C., Camdessanché, J.-P., Camu, W., Cazeneuve, C., Fauret-Amsellem, A.-L., Leguern, E., … Millecamps, S. (2021). Impact of a frequent nearsplice SOD1 variant in amyotrophic lateral sclerosis: Optimising SOD1 genetic screening for gene therapy opportunities. Journal of Neurology, Neurosurgery & Psychiatry, 92(9), 942–949. https://doi.org/10.1136/jnnp-2020-325921
Paris, A., Labrador, B., Lejeune, F.-X., Canlet, C., Molina, J., Guinot, M., Mégret, A., Rieu, M., Thalabard, J.-C., & Le Bouc, Y. (2021). Metabolomic signatures in elite cyclists: Differential characterization of a seeming normal endocrine status regarding three serum hormones. Metabolomics, 17(7), 67. https://doi.org/10.1007/s11306-021-01812-4
Pérez, P., Madsen, J., Banellis, L., Türker, B., Raimondo, F., Perlbarg, V., Valente, M., Niérat, M.-C., Puybasset, L., Naccache, L., Similowski, T., Cruse, D., Parra, L. C., & Sitt, J. D. (2021). Conscious processing of narrative stimuli synchronizes heart rate between individuals. Cell Reports, 36(11), 109692. https://doi.org/10.1016/j.celrep.2021.109692
Poirion, E., Tonietto, M., Lejeune, F.-X., Ricigliano, V. A. G., Boudot de la Motte, M., Benoit, C., Bera, G., Kuhnast, B., Bottlaender, M., Bodini, B., & Stankoff, B. (2021). Structural and Clinical Correlates of a Periventricular Gradient of Neuroinflammation in Multiple Sclerosis. Neurology, 96(14), e1865–e1875. https://doi.org/10.1212/WNL.0000000000011700
Ronzano, R., Roux, T., Thetiot, M., Aigrot, M. S., Richard, L., Lejeune, F. X., Mazuir, E., Vallat, J. M., Lubetzki, C., & Desmazières, A. (2021). Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination. Nature Communications, 12(1), 5219. https://doi.org/10.1038/s41467-021-25486-7
Teyssou, E., Muratet, F., Amador, M.-D.-M., Ferrien, M., Lautrette, G., Machat, S., Boillée, S., Larmonier, T., Saker, S., Leguern, E., Cazeneuve, C., Marie, Y., Guegan, J., Gyorgy, B., Cintas, P., Meininger, V., Le Forestier, N., Salachas, F., Couratier, P., … Millecamps, S. (2021). Genetic screening of ANXA11 revealed novel mutations linked to amyotrophic lateral sclerosis. Neurobiology of Aging, 99, 102.e11-102.e20. https://doi.org/10.1016/j.neurobiolaging.2020.10.015
Wu, M.-Y., Carbo-Tano, M., Mirat, O., Lejeune, F.-X., Roussel, J., Quan, F. B., Fidelin, K., & Wyart, C. (2021). Spinal sensory neurons project onto the hindbrain to stabilize posture and enhance locomotor speed. Current Biology, 31(15), 3315-3329.e5. https://doi.org/10.1016/j.cub.2021.05.042
Zhang, T., Liu, T., Mora, N., Guegan, J., Bertrand, M., Contreras, X., Hansen, A. H., Streicher, C., Anderle, M., Danda, N., Tiberi, L., Hippenmeyer, S., & Hassan, B. A. (2021). Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum. Cell Reports, 35(10), 109208. https://doi.org/10.1016/j.celrep.2021.109208
Zhao, M., Gelize, E., Levy, R., Moulin, A., Azan, F., Berdugo, M., Naud, M.-C., Guegan, J., Delaunay, K., Pussard, E., Lassiaz, P., Bravo-Osuna, I., Herrero-Vanrell, R., & Behar-Cohen, F. (2021). Mineralocorticoid Receptor Pathway and Its Antagonism in a Model of Diabetic Retinopathy. Diabetes, 70(11), 2668–2682. https://doi.org/10.2337/db21-0099
2020
Besse, A., Astord, S., Marais, T., Roda, M., Giroux, B., Lejeune, F.-X., Relaix, F., Smeriglio, P., Barkats, M., & Biferi, M. G. (2020). AAV9-Mediated Expression of SMN Restricted to Neurons Does Not Rescue the Spinal Muscular Atrophy Phenotype in Mice. Molecular Therapy, 28(8), 1887–1901. https://doi.org/10.1016/j.ymthe.2020.05.011
Guesdon, A., Lejeune, F.-X., Rotgé, J.-Y., George, N., & Fossati, P. (2020). Mind-Wandering Changes in Dysphoria. Frontiers in Psychiatry, 11, 544999. https://doi.org/10.3389/fpsyt.2020.544999
Jachiet, M., Bieuvelet, S., Argoud, A. L., Vallée, M., Zinaï, S., Lejeune, F. X., Leger, D., Bouaziz, J. D., Elbaz, M., & Bagot, M. (2020). Sleep disturbance in atopic dermatitis: A case–control study using actigraphy and smartphone‐collected questionnaires. British Journal of Dermatology, 183(3), 577–579. https://doi.org/10.1111/bjd.19058
Lesimple, B., Caron, E., Lefort, M., Debarle, C., Pélégrini-Issac, M., Cassereau, D., Delphine, S., Torkomian, G., Battisti, V., Bossale, P., Galanaud, D., Puybasset, L., Pradat-Diehl, P., & Perlbarg, V. (2020). Long-term cognitive disability after traumatic brain injury: Contribution of the DEX relative questionnaires. Neuropsychological Rehabilitation, 30(10), 1905–1924. https://doi.org/10.1080/09602011.2019.1618345
Marie-Claire, C., Lejeune, F. X., Mundwiller, E., Ulveling, D., Moszer, I., Bellivier, F., & Etain, B. (2020). A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1. Scientific Reports, 10(1), 12239. https://doi.org/10.1038/s41598-020-69073-0
Orts-Del’Immagine, A., Cantaut-Belarif, Y., Thouvenin, O., Roussel, J., Baskaran, A., Langui, D., Koëth, F., Bivas, P., Lejeune, F.-X., Bardet, P.-L., & Wyart, C. (2020). Sensory Neurons Contacting the Cerebrospinal Fluid Require the Reissner Fiber to Detect Spinal Curvature In Vivo. Current Biology, 30(5), 827-839.e4. https://doi.org/10.1016/j.cub.2019.12.071
Prud’hon, S., Bekadar, S., Rastetter, A., Guégan, J., Cormier-Dequaire, F., Lacomblez, L., Mangone, G., You, H., Daniau, M., Marie, Y., Bertrand, H., Lesage, S., Tezenas Du Montcel, S., Anheim, M., Brice, A., Danjou, F., & Corvol, J.-C. (2020). Exome Sequencing Reveals Signal Transduction Genes Involved in Impulse Control Disorders in Parkinson’s Disease. Frontiers in Neurology, 11, 641. https://doi.org/10.3389/fneur.2020.00641
Quan, F. B., Desban, L., Mirat, O., Kermarquer, M., Roussel, J., Koëth, F., Marnas, H., Djenoune, L., Lejeune, F.-X., Tostivint, H., & Wyart, C. (2020). Somatostatin 1.1 contributes to the innate exploration of zebrafish larva. Scientific Reports, 10(1), 15235. https://doi.org/10.1038/s41598-020-72039-x
Thetiot, M., Freeman, S. A., Roux, T., Dubessy, A., Aigrot, M., Rappeneau, Q., Lejeune, F., Tailleur, J., Sol‐Foulon, N., Lubetzki, C., & Desmazieres, A. (2020). An alternative mechanism of early nodal clustering and myelination onset in GABAergic neurons of the central nervous system. Glia, 68(9), 1891–1909. https://doi.org/10.1002/glia.23812
2019
Boisseau W, Euskirchen P, Mokhtari K, Dehais C, Touat M, Hoang-Xuan K, Sanson M, Capelle L, Nouet A, Karachi C, Bielle F, Guégan J, Marie Y, Martin-Duverneuil N, Taillandier L, Rousseau A, Delattre JY, Idbaih A. Molecular Profiling Reclassifies Adult Astroblastoma into Known and Clinically Distinct Tumor Entities with Frequent Mitogen-Activated Protein Kinase Pathway Alterations. Oncologist. 2019 Jul 25. pii: theoncologist.2019-0223. doi:10.1634/theoncologist.2019-0223. [Epub ahead of print] PubMed PMID: 31346129.
Depienne C, Ciura S, Trouillard O, Bouteiller D, Leitão E, Nava C, Keren B, Marie Y, Guégan J, Forlani S, Brice A, Anheim M, Agid Y, Krack P, Damier P, Viallet F, Houeto JL, Durif F, Vidailhet M, Worbe Y, Roze E, Kabashi E, Hartmann A. Association of Rare Genetic Variants in Opioid Receptors with Tourette Syndrome. Tremor Other Hyperkinet Mov (N Y). 2019 Nov 22;9. doi:10.7916/tohm.v0.693. PMID:31824749; PMCID: PMC6878848.
Gendron J, Colace-Sauty C, Beaume N, Cartonnet H, Guégan J, Ulveling D, Pardanaud-Glavieux C, Moszer I, Cheval H, Ravassard P. Long non-coding RNA repertoire and open chromatin regions constitute midbrain dopaminergic neuron-specific molecular signatures. Sci Rep. 2019 Feb 5;9(1):1409. doi:10.1038/s41598-018-37872-1. PubMed PMID: 30723217; PubMed Central PMCID:PMC6363776.
Lesimple B, Caron E, Lefort M, Debarle C, Pélégrini-Issac M, Cassereau D, Delphine S, Torkomian G, Battisti V, Bossale P, Galanaud D, Puybasset L, Pradat-Diehl P, Perlbarg V. Long-term cognitive disability after traumatic brain injury: Contribution of the DEX relative questionnaires. Neuropsychol Rehabil. 2019 May 22:1-20. doi:10.1080/09602011.2019.1618345. Epub ahead of print. PMID:31116085.
Penner G, Lecocq S, Chopin A, Vedoya X, Lista S, Vergallo A, Lejeune FX, Hampel H. Blood-based diagnostics of Alzheimer’s disease. Expert Rev Mol Diagn. 2019 Jul;19(7):613-621. doi: 10.1080/14737159.2019.1626719. Epub 2019 Jun 8. PubMed PMID: 31177871.
Pouzoulet F, Alentorn A, Royer-Perron L, Assayag F, Mokhtari K, Labiod D, Le Garff-Tavernier M, Daniau M, Menet E, Peyre M, Schnitzler A, Guégan J, Davi F, Hoang-Xuan K, Soussain C. Primary CNS lymphoma patient-derived orthotopic xenograft model capture the biological and molecular characteristics of the disease. Blood Cells Mol Dis. 2019 Mar;75:1-10. doi: 10.1016/j.bcmd.2018.11.005. Epub 2018 Nov 16. PubMed PMID: 30502564.
Rohaut B, Doyle KW, Reynolds AS, Igwe K, Couch C, Matory A, Rizvi B, Roh D, Velazquez A, Megjhani M, Park S, Agarwal S, Mauro CM, Li G, Eliseyev A, Perlbarg V, Connolly S, Brickman AM, Claassen J. Deep structural brain lesions associated with consciousness impairment early after hemorrhagic stroke. Sci Rep. 2019 Mar 12;9(1):4174. doi:10.1038/s41598-019-41042-2. PMID: 30862910; PMCID:PMC6414498.
Xicota L, Ichou F, Lejeune FX, Colsch B, Tenenhaus A, Leroy I, Fontaine G, Lhomme M, Bertin H, Habert MO, Epelbaum S, Dubois B, Mochel F, Potier MC; INSIGHT study group. Multi-omics signature of brain amyloid deposition in asymptomatic individuals at-risk for Alzheimer’s disease: The INSIGHT-preAD study. EBioMedicine. 2019 Sep;47:518-528. doi: 10.1016/j.ebiom.2019.08.051. Epub 2019 Sep 3. PubMed PMID: 31492558; PubMed Central PMCID: PMC6796577.
2018
Adanyeguh IM, Perlbarg V, Henry PG, Rinaldi D, Petit E, Valabregue R, Brice A, Durr A, Mochel F. Autosomal dominant cerebellar ataxias: Imaging biomarkers with high effect sizes. Neuroimage Clin. 2018 Jun 14;19:858-867. doi: 10.1016/j.nicl.2018.06.011. eCollection 2018. PubMed PMID: 29922574; PubMed Central PMCID: PMC6005808.
Amador MDM, Masingue M, Debs R, Lamari F, Perlbarg V, Roze E, Degos B, Mochel F. Treatment with chenodeoxycholic acid in cerebrotendinous xanthomatosis: clinical, neurophysiological, and quantitative brain structural outcomes. J Inherit Metab Dis. 2018 Sep;41(5):799-807. doi: 10.1007/s10545-018-0162-7. Epub 2018 Mar 20. PubMed PMID: 29560583.
Bruno A, Labreche K, Daniau M, Boisselier B, Gauchotte G, Royer-Perron L, Rahimian A, Lemoine F, de la Grange P, Guégan J, Bielle F, Polivka M, Adam C, Meyronet D, Figarella-Branger D, Villa C, Chrétien F, Eimer S, Davi F, Rousseau A, Houillier C, Soussain C, Mokhtari K, Hoang-Xuan K, Alentorn A. Identification of novel recurrent ETV6-IgH fusions in primary central nervous system lymphoma. Neuro Oncol. 2018 Jul 5;20(8):1092-1100. doi: 10.1093/neuonc/noy019. PubMed PMID: 29432597.
Debray D, El Mourabit H, Merabtene F, Brot L, Ulveling D, Chrétien Y, Rainteau D, Moszer I, Wendum D, Sokol H, Housset C. Diet-induced dysbiosis and genetic background synergize with cystic fibrosis transmembrane conductance regulator deficiency to promote cholangiopathy in mice. Hepatol Commun. 2018;2(12):1533-1549. doi:10.1002/hep4.1266. PMID: 30556040; PMCID: PMC6287479.
Dréan A, Rosenberg S, Lejeune FX, Goli L, Nadaradjane AA, Guehennec J, Schmitt C, Verreault M, Bielle F, Mokhtari K, Sanson M, Carpentier A, Delattre JY, Idbaih A. ATP binding cassette (ABC) transporters: expression and clinical value in glioblastoma. J Neurooncol. 2018 Jul;138(3):479-486. doi: 10.1007/s11060-018-2819-3. Epub 2018 Mar 8. Erratum in: J Neurooncol. 2018 Mar 16;:. PubMed PMID: 29520610.
Garali I, Adanyeguh IM, Ichou F, Perlbarg V, Seyer A, Colsch B, Moszer I, Guillemot V, Durr A, Mochel F, Tenenhaus A. A strategy for multimodal data integration: application to biomarkers identification in spinocerebellar ataxia. Brief Bioinform. 2018 Nov 27;19(6):1356-1369. doi: 10.1093/bib/bbx060. PubMed PMID: 29106465.
Marie C, Clavairoly A, Frah M, Hmidan H, Yan J, Zhao C, Van Steenwinckel J, Daveau R, Zalc B, Hassan B, Thomas JL, Gressens P, Ravassard P, Moszer I, Martin DM, Lu QR, Parras C. Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8. Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8246-E8255. doi: 10.1073/pnas.1802620115. Epub 2018 Aug 14. PubMed PMID: 30108144; PubMed Central PMCID: PMC6126750.
Parodi L, Fenu S, Barbier M, Banneau G, Duyckaerts C, Tezenas du Montcel S, Monin ML, Ait Said S, Guégan J, Tallaksen CME, Sablonniere B, Brice A, Stevanin G, Depienne C, Durr A; SPATAX network. Spastic paraplegia due to SPAST mutations is modified by the underlying mutation and sex. Brain. 2018 Dec 1;141(12):3331-3342. doi: 10.1093/brain/awy285. PubMed PMID: 30476002.
Perlbarg V, Lambert J, Butler B, Felfli M, Valabrègue R, Privat AL, Lehéricy S, Petiet A. Alterations of the nigrostriatal pathway in a 6-OHDA rat model of Parkinson’s disease evaluated with multimodal MRI. PLoS One. 2018 Sep 6;13(9):e0202597. doi: 10.1371/journal.pone.0202597. eCollection 2018. PubMed PMID: 30188909; PubMed Central PMCID: PMC6126820.
Rudler M, Weiss N, Perlbarg V, Mallet M, Tripon S, Valabregue R, Marjańska M, Cluzel P, Galanaud D, Thabut D. Combined diffusion tensor imaging and magnetic resonance spectroscopy to predict neurological outcome before transjugular intrahepatic portosystemic shunt. Aliment Pharmacol Ther. 2018 Sep 4. doi: 10.1111/apt.14938. PubMed PMID: 30178870.
2017
Delaveau P, Arruda Sanchez T, Steffen R, Deschet K, Jabourian M, Perlbarg V, Gasparetto EL, Dubal S, Costa E Silva J, Fossati P. Default mode and task-positive networks connectivity during the N-Back task in remitted depressed patients with or without emotional residual symptoms. Hum Brain Mapp. 2017 Apr 8. doi: 10.1002/hbm.23603. PubMed PMID: 28390165.
El Behi M, Sanson C, Bachelin C, Guillot-Noël L, Fransson J, Stankoff B, Maillart E, Sarrazin N, Guillemot V, Abdi H, Cournu-Rebeix I, Fontaine B, Zujovic V. Adaptive human immunity drives remyelination in a mouse model of demyelination. Brain. 2017 Apr 1;140(4):967-980. doi: 10.1093/brain/awx008. PubMed PMID: 28334918; PubMed Central PMCID: PMC5382952.
Marsh AP, Heron D, Edwards TJ, Quartier A, Galea C, Nava C, Rastetter A, Moutard ML, Anderson V, Bitoun P, Bunt J, Faudet A, Garel C, Gillies G, Gobius I, Guégan J, Heide S, Keren B, Lesne F, Lukic V, Mandelstam SA, McGillivray G, McIlroy A, Méneret A, Mignot C, Morcom LR, Odent S, Paolino A, Pope K, Riant F, Robinson GA, Spencer-Smith M, Srour M, Stephenson SE, Tankard R, Trouillard O, Welniarz Q, Wood A, Brice A, Rouleau G, Attié-Bitach T, Delatycki MB, Mandel JL, Amor DJ, Roze E, Piton A, Bahlo M, Billette de Villemeur T, Sherr EH, Leventer RJ, Richards LJ, Lockhart PJ, Depienne C. Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance. Nat Genet. 2017 Apr;49(4):511-514. doi: 10.1038/ng.3794. Epub 2017 Feb 27. PubMed PMID: 28250454; PubMed Central PMCID: PMC5894478.
Rosenberg S, Verreault M, Schmitt C, Guégan J, Guehennec J, Levasseur C, Marie Y, Bielle F, Mokhtari K, Hoang-Xuan K, Ligon K, Sanson M, Delattre JY, Idbaih A. Multi-omics analysis of primary glioblastoma cell lines shows recapitulation of pivotal molecular features of parental tumors. Neuro Oncol. 2017 Feb 1;19(2):219-228. doi: 10.1093/neuonc/now160. PubMed PMID: 27571888; PubMed Central PMCID: PMC5463853.
Rosso C, Perlbarg V, Valabregue R, Obadia M, Kemlin-Méchin C, Moulton E, Leder S, Meunier S, Lamy JC. Anatomical and functional correlates of cortical motor threshold of the dominant hand. Brain Stimul. 2017 Sep – Oct;10(5):952-958. doi: 10.1016/j.brs.2017.05.005. Epub 2017 May 17. PubMed PMID: 28551318.
2016
Gargouri F, Messé A, Perlbarg V, Valabregue R, McColgan P, Yahia-Cherif L, Fernandez-Vidal S, Ben Hamida A, Benali H, Tabrizi S, Durr A, Lehéricy S. Longitudinal changes in functional connectivity of cortico-basal ganglia networks in manifests and premanifest huntington’s disease. Hum Brain Mapp. 2016 Nov;37(11):4112-4128. doi: 10.1002/hbm.23299. PubMed PMID: 27400836.
Kraemmer J, Smith K, Weintraub D, Guillemot V, Nalls MA, Cormier-Dequaire F, Moszer I, Brice A, Singleton AB, Corvol JC. Clinical-genetic model predicts incident impulse control disorders in Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2016 Oct;87(10):1106-11. doi: 10.1136/jnnp-2015-312848. Epub 2016 Apr 13. PubMed PMID: 27076492; PubMed Central PMCID: PMC5098340.
Migliaccio R, Gallea C, Kas A, Perlbarg V, Samri D, Trotta L, Michon A, Lacomblez L, Dubois B, Lehericy S, Bartolomeo P. Functional Connectivity of Ventral and Dorsal Visual Streams in Posterior Cortical Atrophy. J Alzheimers Dis. 2016;51(4):1119-30. doi: 10.3233/JAD-150934. PubMed PMID: 26923019.
Operto G, Chupin M, Batrancourt B, Habert MO, Colliot O, Benali H, Poupon C, Champseix C, Delmaire C, Marie S, Rivière D, Pélégrini-Issac M, Perlbarg V, Trebossen R, Bottlaender M, Frouin V, Grigis A, Orfanos DP, Dary H, Fillon L, Azouani C, Bouyahia A, Fischer C, Edward L, Bouin M, Thoprakarn U, Li J, Makkaoui L, Poret S, Dufouil C, Bouteloup V, Chételat G, Dubois B, Lehéricy S, Mangin JF, Cointepas Y; CATI Consortium. CATI: A Large Distributed Infrastructure for the Neuroimaging of Cohorts. Neuroinformatics. 2016 Jul;14(3):253-64. doi: 10.1007/s12021-016-9295-8. Review. PubMed PMID: 27066973.
Richard A, Corvol JC, Debs R, Reach P, Tahiri K, Carpentier W, Guégan J, Guillemot V, Labeyrie C, Adams D, Viala K, Cohen Aubart F. Transcriptome Analysis of Peripheral Blood in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patients Identifies TNFR1 and TLR Pathways in the IVIg Response. Medicine (Baltimore). 2016 May;95(19):e3370. doi: 10.1097/MD.0000000000003370. PubMed PMID: 27175635; PubMed Central PMCID: PMC4902477.
2015
Alentorn A, Durán-Peña A, Malousi A, Marie Y, Mokhtari K, Sanson M, Hoang-Xuan K, Delattre JY, Idbaih A, Vecht C. Differential gene methylation in paired glioblastomas suggests a role of immune response pathways in tumor progression. J Neurooncol. 2015 Sep;124(3):385-92. doi: 10.1007/s11060-015-1869-z. Epub 2015 Jul 30. PubMed PMID: 26224161.
Allaïli N, Valabrègue R, Auerbach EJ, Guillemot V, Yahia-Cherif L, Bardinet E, Jabourian M, Fossati P, Lehéricy S, Marjańska M. Single-voxel (1)H spectroscopy in the human hippocampus at 3 T using the LASER sequence: characterization of neurochemical profile and reproducibility. NMR Biomed. 2015 Oct;28(10):1209-17. doi: 10.1002/nbm.3364. Epub 2015 Aug 18. PubMed PMID: 26282328; PubMed Central PMCID: PMC4573920.
Caroppo P, Habert MO, Durrleman S, Funkiewiez A, Perlbarg V, Hahn V, Bertin H, Gaubert M, Routier A, Hannequin D, Deramecourt V, Pasquier F, Rivaud-Pechoux S, Vercelletto M, Edouart G, Valabregue R, Lejeune P, Didic M, Corvol JC, Benali H, Lehericy S, Dubois B, Colliot O, Brice A, Le Ber I; Predict-PGRN study group. Lateral Temporal Lobe: An Early Imaging Marker of the Presymptomatic GRN Disease? J Alzheimers Dis. 2015;47(3):751-9. doi: 10.3233/JAD-150270. PubMed PMID: 26401709; PubMed Central PMCID: PMC4923734.
Moulton E, Amor-Sahli M, Perlbarg V, Pires C, Crozier S, Galanaud D, Valabregue R, Yger M, Baronnet-Chauvet F, Samson Y, Dormont D, Rosso C. Axial Diffusivity of the Corona Radiata at 24 Hours Post-Stroke: A New Biomarker for Motor and Global Outcome. PLoS One. 2015 Nov 12;10(11):e0142910. doi: 10.1371/journal.pone.0142910. eCollection 2015. PubMed PMID: 26562509; PubMed Central PMCID: PMC4642950.
Nava C, Rupp J, Boissel JP, Mignot C, Rastetter A, Amiet C, Jacquette A, Dupuits C, Bouteiller D, Keren B, Ruberg M, Faudet A, Doummar D, Philippe A, Périsse D, Laurent C, Lebrun N, Guillemot V, Chelly J, Cohen D, Héron D, Brice A, Closs EI, Depienne C. Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders. Amino Acids. 2015 Dec;47(12):2647-58. doi: 10.1007/s00726-015-2057-3. Epub 2015 Jul 28. PubMed PMID: 26215737; PubMed Central PMCID: PMC4633447.