iCONICS operates primarily on a collaborative basis, through scientific partnerships with the requesting teams, leading to co-authorship when the contribution of the platform warrants it.


Besse A, Astord S, Marais T, Roda M, Giroux B, Lejeune FX, Relaix F, Smeriglio P, Barkats M, Biferi MG. AAV9-Mediated Expression of SMN Restricted to Neurons Does Not Rescue the Spinal Muscular Atrophy Phenotype in Mice. Mol Ther. 2020 May 15:S1525-0016(20)30245-8. doi: 10.1016/j.ymthe.2020.05.011. Epub ahead of print. PMID: 32470325.

Jachiet M, Bieuvelet S, Argoud AL, Vallée M, Zinaï S, Lejeune FX, Leger D, Bouaziz JD, Elbaz M, Bagot M. Sleep disturbance in atopic dermatitis: a case-control study using actigraphy and smartphone-collected questionnaires. Br J Dermatol. 2020 Apr 22. doi: 10.1111/bjd.19058. Epub ahead of print. PMID: 32320479.

Marie-Claire C, Lejeune FX, Mundwiller E, Ulveling D, Moszer I, Bellivier F, Etain B. A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1. Sci Rep. 2020 Jul 22;10(1):12239. doi: 10.1038/s41598-020-69073-0. PMID: 32699220; PMCID: PMC7376060.

Thetiot M, Freeman SA, Roux T, Dubessy AL, Aigrot MS, Rappeneau Q, Lejeune FX, Tailleur J, Sol-Foulon N, Lubetzki C, Desmazieres A. An alternative mechanism of early nodal clustering and myelination onset in GABAergic neurons of the central nervous system. Glia. 2020 Sep;68(9):1891-1909. doi: 10.1002/glia.23812. Epub 2020 Mar 2. PMID: 32119167.

Orts-Del’Immagine A, Cantaut-Belarif Y, Thouvenin O, Roussel J, Baskaran A, Langui D, Koëth F, Bivas P, Lejeune FX, Bardet PL, Wyart C. Sensory Neurons Contacting the Cerebrospinal Fluid Require the Reissner Fiber to Detect Spinal Curvature In Vivo. Curr Biol. 2020 Mar 9;30(5):827-839.e4. doi: 10.1016/j.cub.2019.12.071. Epub 2020 Feb 20. PMID: 32084399.


Boisseau W, Euskirchen P, Mokhtari K, Dehais C, Touat M, Hoang-Xuan K, Sanson M, Capelle L, Nouet A, Karachi C, Bielle F, Guégan J, Marie Y, Martin-Duverneuil N, Taillandier L, Rousseau A, Delattre JY, Idbaih A. Molecular Profiling Reclassifies Adult Astroblastoma into Known and Clinically Distinct Tumor Entities with Frequent Mitogen-Activated Protein Kinase Pathway Alterations. Oncologist. 2019 Jul 25. pii: theoncologist.2019-0223. doi:10.1634/theoncologist.2019-0223. [Epub ahead of print] PubMed PMID: 31346129.

Depienne C, Ciura S, Trouillard O, Bouteiller D, Leitão E, Nava C, Keren B, Marie Y, Guégan J, Forlani S, Brice A, Anheim M, Agid Y, Krack P, Damier P, Viallet F, Houeto JL, Durif F, Vidailhet M, Worbe Y, Roze E, Kabashi E, Hartmann A. Association of Rare Genetic Variants in Opioid Receptors with Tourette Syndrome. Tremor Other Hyperkinet Mov (N Y). 2019 Nov 22;9. doi:10.7916/tohm.v0.693. PMID:31824749; PMCID: PMC6878848.

Gendron J, Colace-Sauty C, Beaume N, Cartonnet H, Guégan J, Ulveling D, Pardanaud-Glavieux C, Moszer I, Cheval H, Ravassard P. Long non-coding RNA repertoire and open chromatin regions constitute midbrain dopaminergic neuron-specific molecular signatures. Sci Rep. 2019 Feb 5;9(1):1409. doi:10.1038/s41598-018-37872-1. PubMed PMID: 30723217; PubMed Central PMCID:PMC6363776.

Lesimple B, Caron E, Lefort M, Debarle C, Pélégrini-Issac M, Cassereau D, Delphine S, Torkomian G, Battisti V, Bossale P, Galanaud D, Puybasset L, Pradat-Diehl P, Perlbarg V. Long-term cognitive disability after traumatic brain injury: Contribution of the DEX relative questionnaires. Neuropsychol Rehabil. 2019 May 22:1-20. doi:10.1080/09602011.2019.1618345. Epub ahead of print. PMID:31116085.

Penner G, Lecocq S, Chopin A, Vedoya X, Lista S, Vergallo A, Lejeune FX, Hampel H. Blood-based diagnostics of Alzheimer’s disease. Expert Rev Mol Diagn. 2019 Jul;19(7):613-621. doi: 10.1080/14737159.2019.1626719. Epub 2019 Jun 8. PubMed PMID: 31177871.

Pouzoulet F, Alentorn A, Royer-Perron L, Assayag F, Mokhtari K, Labiod D, Le Garff-Tavernier M, Daniau M, Menet E, Peyre M, Schnitzler A, Guégan J, Davi F, Hoang-Xuan K, Soussain C. Primary CNS lymphoma patient-derived orthotopic xenograft model capture the biological and molecular characteristics of the disease. Blood Cells Mol Dis. 2019 Mar;75:1-10. doi: 10.1016/j.bcmd.2018.11.005. Epub 2018 Nov 16. PubMed PMID: 30502564.

Rohaut B, Doyle KW, Reynolds AS, Igwe K, Couch C, Matory A, Rizvi B, Roh D, Velazquez A, Megjhani M, Park S, Agarwal S, Mauro CM, Li G, Eliseyev A, Perlbarg V, Connolly S, Brickman AM, Claassen J. Deep structural brain lesions associated with consciousness impairment early after hemorrhagic stroke. Sci Rep. 2019 Mar 12;9(1):4174. doi:10.1038/s41598-019-41042-2. PMID: 30862910; PMCID:PMC6414498.

Xicota L, Ichou F, Lejeune FX, Colsch B, Tenenhaus A, Leroy I, Fontaine G, Lhomme M, Bertin H, Habert MO, Epelbaum S, Dubois B, Mochel F, Potier MC; INSIGHT study group. Multi-omics signature of brain amyloid deposition in asymptomatic individuals at-risk for Alzheimer’s disease: The INSIGHT-preAD study. EBioMedicine. 2019 Sep;47:518-528. doi: 10.1016/j.ebiom.2019.08.051. Epub 2019 Sep 3. PubMed PMID: 31492558; PubMed Central PMCID: PMC6796577.


Adanyeguh IM, Perlbarg V, Henry PG, Rinaldi D, Petit E, Valabregue R, Brice A, Durr A, Mochel F. Autosomal dominant cerebellar ataxias: Imaging biomarkers with high effect sizes. Neuroimage Clin. 2018 Jun 14;19:858-867. doi: 10.1016/j.nicl.2018.06.011. eCollection 2018. PubMed PMID: 29922574; PubMed Central PMCID: PMC6005808.

Amador MDM, Masingue M, Debs R, Lamari F, Perlbarg V, Roze E, Degos B, Mochel F. Treatment with chenodeoxycholic acid in cerebrotendinous xanthomatosis: clinical, neurophysiological, and quantitative brain structural outcomes. J Inherit Metab Dis. 2018 Sep;41(5):799-807. doi: 10.1007/s10545-018-0162-7. Epub 2018 Mar 20. PubMed PMID: 29560583.

Bruno A, Labreche K, Daniau M, Boisselier B, Gauchotte G, Royer-Perron L, Rahimian A, Lemoine F, de la Grange P, Guégan J, Bielle F, Polivka M, Adam C, Meyronet D, Figarella-Branger D, Villa C, Chrétien F, Eimer S, Davi F, Rousseau A, Houillier C, Soussain C, Mokhtari K, Hoang-Xuan K, Alentorn A. Identification of novel recurrent ETV6-IgH fusions in primary central nervous system lymphoma. Neuro Oncol. 2018 Jul 5;20(8):1092-1100. doi: 10.1093/neuonc/noy019. PubMed PMID: 29432597.

Debray D, El Mourabit H, Merabtene F, Brot L, Ulveling D, Chrétien Y, Rainteau D, Moszer I, Wendum D, Sokol H, Housset C. Diet-induced dysbiosis and genetic background synergize with cystic fibrosis transmembrane conductance regulator deficiency to promote cholangiopathy in mice. Hepatol Commun. 2018;2(12):1533-1549. doi:10.1002/hep4.1266. PMID: 30556040; PMCID: PMC6287479.

Dréan A, Rosenberg S, Lejeune FX, Goli L, Nadaradjane AA, Guehennec J, Schmitt C, Verreault M, Bielle F, Mokhtari K, Sanson M, Carpentier A, Delattre JY, Idbaih A. ATP binding cassette (ABC) transporters: expression and clinical value in glioblastoma. J Neurooncol. 2018 Jul;138(3):479-486. doi: 10.1007/s11060-018-2819-3. Epub 2018 Mar 8. Erratum in: J Neurooncol. 2018 Mar 16;:. PubMed PMID: 29520610.

Garali I, Adanyeguh IM, Ichou F, Perlbarg V, Seyer A, Colsch B, Moszer I, Guillemot V, Durr A, Mochel F, Tenenhaus A. A strategy for multimodal data integration: application to biomarkers identification in spinocerebellar ataxia. Brief Bioinform. 2018 Nov 27;19(6):1356-1369. doi: 10.1093/bib/bbx060. PubMed PMID: 29106465.

Marie C, Clavairoly A, Frah M, Hmidan H, Yan J, Zhao C, Van Steenwinckel J, Daveau R, Zalc B, Hassan B, Thomas JL, Gressens P, Ravassard P, Moszer I, Martin DM, Lu QR, Parras C. Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8. Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8246-E8255. doi: 10.1073/pnas.1802620115. Epub 2018 Aug 14. PubMed PMID: 30108144; PubMed Central PMCID: PMC6126750.

Parodi L, Fenu S, Barbier M, Banneau G, Duyckaerts C, Tezenas du Montcel S, Monin ML, Ait Said S, Guégan J, Tallaksen CME, Sablonniere B, Brice A, Stevanin G, Depienne C, Durr A; SPATAX network. Spastic paraplegia due to SPAST mutations is modified by the underlying mutation and sex. Brain. 2018 Dec 1;141(12):3331-3342. doi: 10.1093/brain/awy285. PubMed PMID: 30476002.

Perlbarg V, Lambert J, Butler B, Felfli M, Valabrègue R, Privat AL, Lehéricy S, Petiet A. Alterations of the nigrostriatal pathway in a 6-OHDA rat model of Parkinson’s disease evaluated with multimodal MRI. PLoS One. 2018 Sep 6;13(9):e0202597. doi: 10.1371/journal.pone.0202597. eCollection 2018. PubMed PMID: 30188909; PubMed Central PMCID: PMC6126820.

Rudler M, Weiss N, Perlbarg V, Mallet M, Tripon S, Valabregue R, Marjańska M, Cluzel P, Galanaud D, Thabut D. Combined diffusion tensor imaging and magnetic resonance spectroscopy to predict neurological outcome before transjugular intrahepatic portosystemic shunt. Aliment Pharmacol Ther. 2018 Sep 4. doi: 10.1111/apt.14938. PubMed PMID: 30178870.


Delaveau P, Arruda Sanchez T, Steffen R, Deschet K, Jabourian M, Perlbarg V, Gasparetto EL, Dubal S, Costa E Silva J, Fossati P. Default mode and task-positive networks connectivity during the N-Back task in remitted depressed patients with or without emotional residual symptoms. Hum Brain Mapp. 2017 Apr 8. doi: 10.1002/hbm.23603. PubMed PMID: 28390165.

El Behi M, Sanson C, Bachelin C, Guillot-Noël L, Fransson J, Stankoff B, Maillart E, Sarrazin N, Guillemot V, Abdi H, Cournu-Rebeix I, Fontaine B, Zujovic V. Adaptive human immunity drives remyelination in a mouse model of demyelination. Brain. 2017 Apr 1;140(4):967-980. doi: 10.1093/brain/awx008. PubMed PMID: 28334918; PubMed Central PMCID: PMC5382952.

Marsh AP, Heron D, Edwards TJ, Quartier A, Galea C, Nava C, Rastetter A, Moutard ML, Anderson V, Bitoun P, Bunt J, Faudet A, Garel C, Gillies G, Gobius I, Guégan J, Heide S, Keren B, Lesne F, Lukic V, Mandelstam SA, McGillivray G, McIlroy A, Méneret A, Mignot C, Morcom LR, Odent S, Paolino A, Pope K, Riant F, Robinson GA, Spencer-Smith M, Srour M, Stephenson SE, Tankard R, Trouillard O, Welniarz Q, Wood A, Brice A, Rouleau G, Attié-Bitach T, Delatycki MB, Mandel JL, Amor DJ, Roze E, Piton A, Bahlo M, Billette de Villemeur T, Sherr EH, Leventer RJ, Richards LJ, Lockhart PJ, Depienne C. Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance. Nat Genet. 2017 Apr;49(4):511-514. doi: 10.1038/ng.3794. Epub 2017 Feb 27. PubMed PMID: 28250454; PubMed Central PMCID: PMC5894478.

Rosenberg S, Verreault M, Schmitt C, Guégan J, Guehennec J, Levasseur C, Marie Y, Bielle F, Mokhtari K, Hoang-Xuan K, Ligon K, Sanson M, Delattre JY, Idbaih A. Multi-omics analysis of primary glioblastoma cell lines shows recapitulation of pivotal molecular features of parental tumors. Neuro Oncol. 2017 Feb 1;19(2):219-228. doi: 10.1093/neuonc/now160. PubMed PMID: 27571888; PubMed Central PMCID: PMC5463853.

Rosso C, Perlbarg V, Valabregue R, Obadia M, Kemlin-Méchin C, Moulton E, Leder S, Meunier S, Lamy JC. Anatomical and functional correlates of cortical motor threshold of the dominant hand. Brain Stimul. 2017 Sep – Oct;10(5):952-958. doi: 10.1016/j.brs.2017.05.005. Epub 2017 May 17. PubMed PMID: 28551318.


Gargouri F, Messé A, Perlbarg V, Valabregue R, McColgan P, Yahia-Cherif L, Fernandez-Vidal S, Ben Hamida A, Benali H, Tabrizi S, Durr A, Lehéricy S. Longitudinal changes in functional connectivity of cortico-basal ganglia networks in manifests and premanifest huntington’s disease. Hum Brain Mapp. 2016 Nov;37(11):4112-4128. doi: 10.1002/hbm.23299. PubMed PMID: 27400836.

Kraemmer J, Smith K, Weintraub D, Guillemot V, Nalls MA, Cormier-Dequaire F, Moszer I, Brice A, Singleton AB, Corvol JC. Clinical-genetic model predicts incident impulse control disorders in Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2016 Oct;87(10):1106-11. doi: 10.1136/jnnp-2015-312848. Epub 2016 Apr 13. PubMed PMID: 27076492; PubMed Central PMCID: PMC5098340.

Migliaccio R, Gallea C, Kas A, Perlbarg V, Samri D, Trotta L, Michon A, Lacomblez L, Dubois B, Lehericy S, Bartolomeo P. Functional Connectivity of Ventral and Dorsal Visual Streams in Posterior Cortical Atrophy. J Alzheimers Dis. 2016;51(4):1119-30. doi: 10.3233/JAD-150934. PubMed PMID: 26923019.

Operto G, Chupin M, Batrancourt B, Habert MO, Colliot O, Benali H, Poupon C, Champseix C, Delmaire C, Marie S, Rivière D, Pélégrini-Issac M, Perlbarg V, Trebossen R, Bottlaender M, Frouin V, Grigis A, Orfanos DP, Dary H, Fillon L, Azouani C, Bouyahia A, Fischer C, Edward L, Bouin M, Thoprakarn U, Li J, Makkaoui L, Poret S, Dufouil C, Bouteloup V, Chételat G, Dubois B, Lehéricy S, Mangin JF, Cointepas Y; CATI Consortium. CATI: A Large Distributed Infrastructure for the Neuroimaging of Cohorts. Neuroinformatics. 2016 Jul;14(3):253-64. doi: 10.1007/s12021-016-9295-8. Review. PubMed PMID: 27066973.

Richard A, Corvol JC, Debs R, Reach P, Tahiri K, Carpentier W, Guégan J, Guillemot V, Labeyrie C, Adams D, Viala K, Cohen Aubart F. Transcriptome Analysis of Peripheral Blood in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patients Identifies TNFR1 and TLR Pathways in the IVIg Response. Medicine (Baltimore). 2016 May;95(19):e3370. doi: 10.1097/MD.0000000000003370. PubMed PMID: 27175635; PubMed Central PMCID: PMC4902477.


Alentorn A, Durán-Peña A, Malousi A, Marie Y, Mokhtari K, Sanson M, Hoang-Xuan K, Delattre JY, Idbaih A, Vecht C. Differential gene methylation in paired glioblastomas suggests a role of immune response pathways in tumor progression. J Neurooncol. 2015 Sep;124(3):385-92. doi: 10.1007/s11060-015-1869-z. Epub 2015 Jul 30. PubMed PMID: 26224161.

Allaïli N, Valabrègue R, Auerbach EJ, Guillemot V, Yahia-Cherif L, Bardinet E, Jabourian M, Fossati P, Lehéricy S, Marjańska M. Single-voxel (1)H spectroscopy in the human hippocampus at 3 T using the LASER sequence: characterization of neurochemical profile and reproducibility. NMR Biomed. 2015 Oct;28(10):1209-17. doi: 10.1002/nbm.3364. Epub 2015 Aug 18. PubMed PMID: 26282328; PubMed Central PMCID: PMC4573920.

Caroppo P, Habert MO, Durrleman S, Funkiewiez A, Perlbarg V, Hahn V, Bertin H, Gaubert M, Routier A, Hannequin D, Deramecourt V, Pasquier F, Rivaud-Pechoux S, Vercelletto M, Edouart G, Valabregue R, Lejeune P, Didic M, Corvol JC, Benali H, Lehericy S, Dubois B, Colliot O, Brice A, Le Ber I; Predict-PGRN study group. Lateral Temporal Lobe: An Early Imaging Marker of the Presymptomatic GRN Disease? J Alzheimers Dis. 2015;47(3):751-9. doi: 10.3233/JAD-150270. PubMed PMID: 26401709; PubMed Central PMCID: PMC4923734.

Moulton E, Amor-Sahli M, Perlbarg V, Pires C, Crozier S, Galanaud D, Valabregue R, Yger M, Baronnet-Chauvet F, Samson Y, Dormont D, Rosso C. Axial Diffusivity of the Corona Radiata at 24 Hours Post-Stroke: A New Biomarker for Motor and Global Outcome. PLoS One. 2015 Nov 12;10(11):e0142910. doi: 10.1371/journal.pone.0142910. eCollection 2015. PubMed PMID: 26562509; PubMed Central PMCID: PMC4642950.

Nava C, Rupp J, Boissel JP, Mignot C, Rastetter A, Amiet C, Jacquette A, Dupuits C, Bouteiller D, Keren B, Ruberg M, Faudet A, Doummar D, Philippe A, Périsse D, Laurent C, Lebrun N, Guillemot V, Chelly J, Cohen D, Héron D, Brice A, Closs EI, Depienne C. Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders. Amino Acids. 2015 Dec;47(12):2647-58. doi: 10.1007/s00726-015-2057-3. Epub 2015 Jul 28. PubMed PMID: 26215737; PubMed Central PMCID: PMC4633447.